Chondrosamine® Plus MSM

250g / 500g Powder
AUST L 165656

Nutritional Support for Healthy Joints

Glucosamine sulfate and chondroitin sulfate support the maintenance of healthy joints through their role in the synthesis of joint matrix structural components. Along with methylsulfonylmethane (MSM), vitamin C and trace minerals provide nutritional support for connective tissue.

At a Glance

Key Features and Benefits
Product Formula
Directions for Use
Safety Information
Frequently Asked Questions
Did You Know?

Introduction

Arthritis is characterised by joint inflammation and cartilage tissue breakdown. Osteoarthritis is caused by the degeneration of cartilage. Cartilage has a gel-like nature and protects the ends of the joints in the body by acting as a shock absorber. Without cartilage in the joint, bone literally rubs against bone leading to inflammation, pain, deformity, and limitation of movement in the joint.

Glucosamine sulfate provides nutritional support for the metabolism and repair of joints and cartilage.

Chondroitin sulfate is a glycosaminoglycan which is a fundamental component of cartilage and other connective tissue.

MSM is a natural source of sulfur which has many structural and functional roles in the body. It is required for healthy development and maintenance of connective tissue and is a component of the antioxidant compounds N-acetylcysteine and glutathione.

Vitamin C and minerals such as magnesium, potassium, and zinc provide additional nutritional support for healthy connective tissue and bone mineralisation.

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Key Features and Benefits

  • May provide symptomatic relief of joint pain associated with osteoarthritis.
  • May help to reduce joint swelling associated with arthritis.
  • May help to increase joint mobility.
  • May assist in the management of osteoarthritis.
  • May help to slow the progression of osteoarthritis of the knee.
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Product Formula

Each Dose (6g) Contains:
Glucosamine sulfate-potassium chloride complex 1g
  equiv. glucosamine sulfate 750mg
Dimethyl sulfone (methylsulfonylmethane - MSM) 750mg
Chondroitin sulfate 250mg
Vitamins:
Calcium ascorbate 329mg
  equiv. ascorbic acid (vitamin C) 272mg
Minerals:
Magnesium (as aspartate) 13.2mg
Potassium (as aspartate) 36.3mg
Zinc (as amino acid chelate) 5mg
Manganese (as amino acid chelate) 1.5mg
Copper (as gluconate) 500ug
Nutrients:
Hesperidin 150mg
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Directions for Use

Adults: Mix 1 to 2 scoops (1 scoop = 6g) into 200 mL of water or juice. Consume two to three times daily, or as directed by your healthcare professional.

Safety Information

  • Contains potassium. If you have kidney disease or are taking heart or blood pressure medications – consult your pharmacist or doctor before use.
  • If symptoms persist, consult your healthcare professional.
  • The use of glucosamine sulfate, chondroitin sulfate and MSM during pregnancy and lactation has not been scientifically evaluated.
  • Certain nutrients have been found to enhance the way some medications work and help make other medications safer. Please consult your pharmacist for further information.
  • Contraindicated in patients with shellfish allergy.

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Frequently Asked Questions

Is it safe for me to take supplements with my current medications?

In many cases it is safe to combine nutritional supplements with pharmaceutical medications; however, there are always exceptions. Always seek the advice of a qualified healthcare professional before adding a supplement to an existing regime.

I’m vegetarian. Is Chondrosamine® Plus MSM suitable for me?

Glucosamine is derived from the exoskeletons of shellfish such as prawns, lobsters and crabs, while the chondroitin is derived from shark cartilage. Therefore Chondrosamine® Plus MSM is not suitable for vegetarians.

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Did You Know?

  1. Glucosamine sulfate and chondroitin sulfate not only assist in relieving the symptoms of arthritis, but may also slow the progression of osteoarthritis.7

References

1Pavelká K, Gatterová J, Olejarová M, Machacek S, Giacovelli G, Rovati LC. Glucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind study. Arch Intern Med 2002 Oct 14;162(18):2113-2123.

2.Reginster JY, Deroisy R, Rovati LC, Lee RL, Lejeune E, Bruyere O, et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Lancet 2001 Jan 27;357(9252):251-256.

3Scroggie DA, Albright A, Harris MD. The effect of glucosamine-chondroitin supplementation on glycosylated hemoglobin levels in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial. Arch Intern Med 2003 Jul 14;163(13):1587-1590.

4Yu JG, Boies SM, Olefsky JM. The effect of oral glucosamine sulfate on insulin sensitivity in human subjects. Diabetes Care 2003 Jun;26(6):1941-1942.

5Conte A, de Bernardi M, Palmieri L, Lualdi P, Mautone G, Ronca G. Metabolic fate of exogenous chondroitin sulfate in man. Arzneimittelforschung 1991 Jul;41(7):768-772.

6Morrison LM, Enrick N. Coronary heart disease: reduction of death rate by chondroitin sulfate A. Angiology 1973 May; 24(5):269-287.

7Parcell S. Sulfur in human nutrition and applications in medicine. Altern Med Rev 2002 Feb;7(1):22-44.

8Braun L , Cohen M. Herbs and natural supplements: An evidence-based guide, 2nd ed. Sydney: Churchill Livingstone Elsevier, 2007.

9.Kelly GS. The role of glucosamine sulfate and chondroitin sulfates in the treatment of degenerative joint disease. Altern Med Rev 1998 Feb; 3(1):27-39.

10Pizzorno JE JR, Murray MT. Textbook of natural medicine, 3rd ed. St Louis: Churchill Livingstone Elsevier, 2006.

11Van der Kraan PM, Vitters EL, de Vries BJ, van den Berg WB. High susceptibility of human articular cartilage glycosaminoglycan synthesis to changes in inorganic sulfate availability. J Orthop Res 1990 Jul;8(4):565-57

12Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage 2006 Mar;14(3):286-294.

13Tortora GJ, Grabowski SR. Principles of anatomy and physiology, 10th ed. New York: John Wiley & Sons, 2003

14Brody T. Nutritional biochemistry, 2nd ed. San Diego: Academic Press, 1999.

15Usha PR, Haidu MU. Randomised, double-blind, parallel, placebo-controlled study of oral glucosamine, methylsulfonylmethane and their combination in osteoarthritis. Clin Drug Investig 2004;24(6):353-363.

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